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INTRODUCTION

Clinically significant ovarian hyperstimulation syndrome is the most serious potential problem occurring as a result of ovulation induction either for IVF or for Superovulation-IUI. This syndrome can develop in 3–5 % of patients.

WHAT ARE THE SYMPTOMS OF OHSS?

The symptoms that may be experienced include:

  1. A bloated feeling
  2. Abdominal discomfort
  3. Nausea
  4. Vomiting
  5. In extreme cases – difficulty breathing

WHO IS AT RISK OF OHSS?

  1. OHSS is a small risk for all patients having superovulation treatment. Patients at most risk of OHSS are those with polycystic ovarian syndrome (PCOS).

TREATMENT :

In some circumstances it might be necessary to drain some fluid from the abdomen. This can be done by passing a fine needle either through the vagina or abdominal wall (under ultrasound guidance) and draining the fluid. This fluid is rich in protein, and it might be necessary to replenish that protein by giving you an intravenous infusion of Albumin.

Because of the increased risk of thrombosis, you may be asked to start taking a blood thinner called heparin. This is given by twice daily subcutaneous injections.